Set largely in the dark backwoods just outside of New Orleans, The Skeleton Key stars Hudson as Caroline, a live-in nurse hired to care for an elderly woman's (Rowlands) ailing husband (Hurt) in their home...a foreboding and decrepit mansion in the Louisiana delta. Intrigued by the enigmatic couple and their rambling house, Caroline beings to explore the old mansion. Armed with a skeleton key that unlocks every door, she discovers a hidden attic room that holds a deadly and terrifying secret.


　　凯特·哈德森饰演的私人护士卡罗琳被一名老妇雇佣照顾她年老病弱的丈夫，她来到路易斯安纳的一座古老的大宅子中。很快，卡罗琳就发现，不管是这对诡黠神秘的老夫妻，还是这栋阴森压抑的大宅，都仿佛隐藏着无数的秘密，于是卡罗琳拿着一把可以打开所有门锁的万能钥匙，开始“探险”，就在她打开顶层一个隐秘的阁楼房门后，所有惊人的、恐怖的、难以想像的秘密展现在她眼前……